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1 Lung cancer can be broadly classified into 2 types: small cell lung cancer (SCLC) and non-SCLC (NSCLC).
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Lung cancer is the leading cause of cancer-related mortality in the US, with 228 150 new cases and 142 670 deaths in 2019. Role of the Funder/Sponsor: The funder had no role in the design and conduct of the study collection, management, analysis, and interpretation of the data preparation, review, or approval of the manuscript and decision to submit the manuscript for publication. No other disclosures were reported.įunding/Support: This study was supported by the National Cancer Institute (grant K12CA090628 to Dr Lou). Dr Lou reported serving on the advisory boards of AstraZeneca and Novocure receiving an honorarium from Clarion Health Care and receiving research funding support from Merck, MacroGenics, Tolero Pharmaceuticals, AstraZeneca, Vaccinex, Blueprint Medicines, Harpoon Therapeutics, Sun Pharma Advanced Research, Bristol-Myers Squibb, Kyowa Pharmaceuticals, Tesaro, and Bayer HealthCare. Dr Ailawadhi reported receiving grants from Janssen, Amgen, Cellectar, Ascentage, and AstraZeneca and personal fees from Takeda, BMS, GSK, and Beigene outside the submitted work. Dr Manochakian reported receiving personal fees from AstraZeneca, Novocure, Guardant Health, and Takeda outside the submitted work. Statistical analysis: Chen, Cochuyt, Hodge, Ailawadhi.Īdministrative, technical, or material support: Zhou, Shi, Chen.Ĭonflict of Interest Disclosures: Ms Chen reported that her spouse is employed by Gilead Sciences and that she holds stocks in Eli Lilly. Drs Zhou and Shi contributed equally to this work.Ĭoncept and design: Zhou, Shi, Chen, Manochakian, Ailawadhi, Lou.Īcquisition, analysis, or interpretation of data: Shi, Chen, Cochuyt, Hodge, Manochakian, Zhao, Ailawadhi.ĭrafting of the manuscript: Zhou, Chen, Manochakian, Ailawadhi.Ĭritical revision of the manuscript for important intellectual content: Shi, Chen, Cochuyt, Hodge, Manochakian, Zhao, Ailawadhi, Lou.
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Corresponding Author: Yanyan Lou, MD, PhD, Division of Hematology and Medical Oncology, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224 ( Contributions: Dr Lou had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.